• Whole body CT only showed mild

  2019-06-27

  

  Whole-body CT only showed mild splenomegaly (14cm) and an enlarged iliac lymph node (1.5×3cm). Cranial MR yielded no specific findings. In the meantime, the patient was given Rituximab. He received 375mg/m2 of Rituximab per week, but after the third dose the patient rapidly developed shock and abdo

• br Discussion Our results confirm that germline

  2019-06-27

  

  Discussion Our results confirm that germline variations in the TPMT gene are associated with treatment outcome in children with ALL [5]. The ability of TPMT to catalyze S-methylation and inactivate 6-mercaptopurine makes it a major determinant of 6-mercaptopurine toxicity. Furthermore, reduced TP

• The CONNECT trial conducted by Crossley et

  2019-06-27

  

  The CONNECT trial conducted by Crossley et al. [22] was also a multicenter, prospective, randomized evaluation of wireless RM, which included 1997 patients implanted with ICDs or CRT-Ds. They were randomly assigned to the remote or in-office groups and followed up for 15 months. The median time from

• Programmed death ligand PD L expression

  2019-06-27

  

  Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed

• br Meses m s tarde en

  2019-06-27

  

  Meses más tarde, en “Un monosindicato que se adhiere AS 602801 of las huelgas” (, 14/enero/1935), Max Carón incluye un pliego petitorio donde delata y, a la vez, desvirtúa la profesión de su alter ego, la de traductor de cables del inglés y del francés: “Obligación de Gilberto Owen (el señor de la

• br zoonoses are responsible for

  2019-06-27

  

  13 zoonoses are responsible for a staggering 2·2 billion human illnesses and 2·3 million deaths per year, mostly in low-income and middle-income countries () where the correlation between rates of protein malnutrition and incidence of endemic zoonotic diseases is 99%. Veterinary medicine has an i

• Selection of a Practice-based Intervention En este exordio d

  2019-06-26

  

  En este exordio de la carta, hoy perdida, que acompañaba la obra de Pané, se expresan todas las dudas del Almirante que, a pesar de la hipótesis de la ausencia de idolatría entre los taínos (interpretación esencial para ofrecer una representación de los indígenas que justificara su dominio), se most

• Brasil ha sido el principal

  2019-06-26

  

  Brasil ha sido el principal país de origen de las importaciones argentinas hasta el punto que en 2011 tales importaciones del vecino sumaron más de 21 000 millones de dólares. Es cierto que la compra de productos brasileños fue disminuyendo desde 2003, que representaba 34% del total de las importaci

• Consequently in asymptomatic individuals multiple and

  2019-06-26

  

  Consequently, in asymptomatic individuals, multiple and repeated ECG recordings rather than drug testing are recommended for detecting the transient appearance of a spontaneous type 1 ECG, which may indicate the future development of arrhythmic events. Moreover, in addition recording at higher lead

• The pre procedural venogram showed

  2019-06-26

  

  The pre-procedural venogram showed total occlusion of the left BCV and the formation of an acute angle between the right BCV and SVC caused by tuberculosis-induced lung destruction (Fig. 1A and B). We adopted a right-sided venous approach via the right subclavian vein (SCV) for a single chamber. Ini

• Catheter ablation was performed from

  2019-06-26

  

  Catheter ablation was performed from the basal septum to the apex in the sites where the right bundle branch potential could be recorded. Radiofrequency (RF) Fmoc-Asp(OtBu)-OH weight was delivered with a temperature controlled 4-mm-tip deflectable catheter (Biosense Webster, Diamond Bar, CA, USA) w

• br As the only methods available for dual protection

  2019-06-26

  

  As the only methods available for dual protection against pregnancy and sexually transmitted infections (STIs), male and female condoms have a vital role in sexual and reproductive health. Mags Beksinska and colleagues therefore are to be commended for their randomised crossover trial in this TMC

• br This year marks years since countries

  2019-06-26

  

  This year marks 20 years since 189 countries signed the Beijing Declaration and Platform for Action and committed to prioritisation of women\'s empowerment and gender equality. Yet a recently released UN analysis shows that violence against women persists at “alarmingly high levels”. Worldwide, on

• Desde el primer momento los protagonistas de la exploraci n

  2019-06-26

  

  Desde el primer momento, los protagonistas de la exploración del Caribe mostraron grandes dificultades para comprender la “inusitada” religiosidad indígena. Al igual que los demás aspectos de las culturas indígenas, la religión de los taínos fue representada por medio de una “retórica de la ausencia

• Hydroxyurea what Uno de los rasgos m s in http www apexbt

  2019-06-26

  

  Uno de los rasgos más interesantes que encontramos en este retrato (figura 1) es la madurez y prolijidad que Portinari Hydroxyurea what en unos cabellos bien peinados —aunque con unas entradas muy pronunciadas y unas patillas perfectamente recortadas— en la piel marcada por el paso del tiempo, no o

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