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Patients with heart failure are at
2019-04-30
Patients with heart failure are at a high risk of mortality and morbidity. Medical expenses associated with heart failure are increasing, and approaches aimed at early heart failure detection and reduction of the hospitalization rate are yet to be developed. Patients with CIEDs also develop heart fa
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Since many decades bone tumours have
2019-04-30
Since many decades, bone tumours have stimulated imagination of researchers and numerous therapeutic alternatives have been proposed [134,135, Fig. 4]. The better knowledge of OPG/RANK/RANKL system leads to the development of peptides mimicking OPG and blocking RANK–RANKL interactions [136–139]. Inh
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br Discussion HIV testing and linkage to care are essential
2019-04-30
Discussion HIV testing and linkage to care are essential for fighting the HIV epidemic, and evidence-based methods for increasing coverage of testing and accelerating linkage to care are needed. We report that abbreviated counselling was as effective as full length counselling in reducing sexual
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neuronal metabolism Through analyses of data from surveys th
2019-04-30
Through analyses of data from surveys that used similar measures, methods, and ethical standards across 44 countries, Heise and Kotsadam have taken an important step towards an improved understanding of intimate partner violence and informing interventions. However, much work remains to be done. In
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The S helix of KCNQ consists of
2019-04-29
The S4 helix of KCNQ1 consists of a peculiar sequence of positively charged our site forming a region that is involved in sensing the membrane voltage and controlling the open probability of the channel [27]. In the resting state of the channel, these positively charged side chains are expected to b
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br It is now just more than
2019-04-29
It is now just more than a year since the official confirmation of an outbreak of Ebola haemorrhagic fever in west Africa. With new cases occurring at their lowest rate for 2015, and the end of the outbreak in sight for all three countries predominantly affected, now is the time to consider strate
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On December the patient was started on ruxolitinib mg twice
2019-04-29
On December 2013 the patient was started on ruxolitinib 10mg twice a day (day 0). His dose was increased to 15mg twice a day on day +57 and to 20mg twice a day on day +84. He was tapered off hydroxyurea and was completely off on day +14. As shown in Fig. 1A, the WBC and MCV were reduced gradually o
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droperidol The prevalence of pathological fracture was in th
2019-04-29
The prevalence of pathological fracture was 32.9% in this study, and a significantly higher prevalence of simple fracture was observed in women (26.3%) than in men (15.2%). This sex difference may be partly explained by the lower weights of bones in women than in men. Indeed, we observed that the fe
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It is well known that elevated intracellular cAMP concentrat
2019-04-29
It is well known that elevated intracellular cAMP concentrations and enhanced catecholamine signaling stimulate the β2-adrenergic receptors on adipose tissue to increase lipolysis. Surprisingly, previous work from Dr. Nagy\'s group revealed that chronic ethanol intake suppressed beta-adrenergic rece
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In Nigeria sufficient funds can be
2019-04-29
In Nigeria, sufficient funds can be obtained through sin taxes on products that Etoposide pose risk to health, such as tobacco and alcohol, progressive levies on phone calls or mobile phone purchases, and taxes on air tickets, foreign exchange transactions, and luxury goods. Nigeria could also gener
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La noci n de subversi n
2019-04-29
La noción de “subversión” de ascendencia francesa apareció por primera vez en un conjunto de normas publicado en el Boletín Oficial en septiembre de 1973, mediante el “Acta de compromiso de la seguridad nacional” y la creación del Consejo de Seguridad Nacional que coordinaba la acción policial con l
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En el segundo caso la
2019-04-29
En el segundo caso, la España republicana se constituye como un espejo quebrado, aquello destruido, perdido y que es mejor olvidar para atender la historia urgente y presente del territorio latinoamericano, de muestra vale el ejemplo citado que refiere purchase ABT-263 la importancia de centrar las
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Nintedanib A critical link exists between awareness of risk
2019-04-29
A critical link exists between awareness of risk, the presence of disease, and steps taken by the patient and clinician to change the natural history of disease. Chronic illnesses such as diabetes mellitus, dyslipidaemia, anaemia and a multitude of endocrinological and rheumatological diseases are r
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BMD of the spine but not at the hip
2019-04-28
BMD of the spine, but not at the hip, demonstrated a significant increase of 6.3%, p=0.02 at 3 years in the osteopaenic group receiving early intervention with alendronate. However, we did not demonstrate an improvement in BMD for the osteopaenic group receiving late intervention with alendronate. P
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Ahora bien lejos de cuestionar la forma libro para arrojarse
2019-04-28
Ahora bien, lejos de cuestionar la forma libro para arrojarse plácidamente en brazos de un arte al uso, “estos libros son, por su existencia misma —remarca Anne Moegelin-Delcroix—, una crítica de la concepción tradicional de obra de arte en la medida en que persiguen hacer compatible la creación con
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