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In conclusion adipose PGD suppressed the lipolysis by decrea
2020-07-28
In conclusion, adipose PGD2 suppressed the lipolysis by decreasing the intracellular cAMP level through DP2R. Therefore, PGD2 enhanced adipocyte differentiation (lipid accumulation) through both repression of the lipolysis via DP2R and activation of the lipogenesis via PPARγ. Thus, L-PGDS and DP2R a
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Adrenocortical steroids release by the
2020-07-28
Adrenocortical steroids release by the adrenal gland is directly regulated by CRF (Nussdorfer, 1996) through its receptors, predominantly CRF1r (Müller et al., 2001). In the adrenal gland, PFOS at the dose of 0.5 mg/kg/day activates CRF1r gene expression while the doses of 3.0 and 6.0 mg/kg/day stim
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Several different information items can be recommended
2020-07-28
Several different information items can be recommended to support the software engineer in his/her task according to his/her needs. These items types include source code within a project, reusable source code, code examples, operations and people (Robillard et al., 2014). We witness several works on
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Finally the presence of the
2020-07-28
Finally, the presence of the recombinant hydroxylated sponge collagen polypeptide was detected in the colCH4 strain by MS-analysis using a TripleTOF instrument and allowing to confirm the ability of the recombinant sponge P4H to display its catalytic activity inside the yeast cell on its natural sub
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Chemical cytometry utilizes sensitive analytical techniques
2020-07-27
Chemical cytometry utilizes sensitive analytical techniques such as microelectrophoresis or mass spectrometry to analyze and characterize the contents of single autumn wind (Dovichi, 2010; Dovichi & Hu, 2003). Microelectrophoretic chemical cytometry is well-suited to address many of the challenges
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Fig shows optical microscopy images of the nanocomposite
2020-07-27
Fig. 1 shows optical microscopy images of the nanocomposite surfaces at increasing concentration of GNP-DNA filler, indicating a clear improvement of the surface homogeneity at higher loading. Larger 46619 australia are present in the nanocomposite with 20 wt% of GNP-DNA with brighter and darker re
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br New methods to investigate responses at
2020-07-27
New methods to investigate responses at low-dose exposures Alkylating agents DNA repair and break point doses Interactions between DNA repair and DDR pathways Profiling of biological pathways and genotoxic dose–response relationships Conclusions There is significant interest in und
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L AmDH and parent LeuDH
2020-07-27
L-AmDH and parent LeuDH differed in response to increasing solution viscosity, indicating a change in the rate-limiting steps of catalysis. For LeuDH, both the amination and deamination directions showed an inverse hyperbolic viscosity effect on normalized appkcat/KM value for the amino/amino (±)-J
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Our studies investigating a role for integrins in collagen
2020-07-27
Our studies investigating a role for integrins in collagen induction of lysyl oxidase may also suggest a cooperative function for integrins in DDR2-mediated up-regulation of lysyl oxidase by collagen. It is interesting to note, however, that the level of 32kDa lysyl oxidase in the presence of EDTA w
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br DDR receptor in cross
2020-07-27
DDR2 receptor in cross talking mechanism at joints Cross talking pathway provides us a better understanding of the chondrocytes behavior as chondrocytes expressed several receptors that get activated by components of an extracellular matrix upon damage in articular cartilage. DDR2 receptor in OA
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br Acknowledgments The authors thank Elisabete Lepera and
2020-07-27
Acknowledgments The authors thank Elisabete Lepera and Rosana Silva for technical support. The study was supported by FAPESP, CNPq and PADC/FCF-UNESP. T.T. Miguel was the recipient of a FAPESP (Proc. 05/05171-1) and R.L. Nunes-de-Souza of a CNPq (Proc. 303580/2009-7) fellowship. Introduction
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The conditioned place aversion CPA paradigm is
2020-07-27
The conditioned-place aversion (CPA) paradigm is a highly sensitive animal model for measurement of the negative affective component of drug withdrawal, as well as for investigating neural substrates underlying the aversive memory associated with withdrawal (Myers et al., 2012; Stinus et al., 2000).
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Most diagnostic tests for the detection of Aspergillus and o
2020-07-27
Most diagnostic tests for the detection of Aspergillus and other fungi utilise serum and bronchoalveolar lavage (BAL) fluid for the confirmation of pulmonary aspergillosis and acute invasive aspergillosis (Agarwal et al., 2015). BAL requires bronchoscopy that is invasive and may be difficult to obta
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br Materials and methods br Results br Discussion
2020-07-25
Materials and methods Results Discussion In our tissue array, we demonstrated that 14-3-3 tau mRNA and protein expression levels decreased in the preeclamptic placentas. 14-3-3 proteins are considered to be important in the functional regulation of trophoblasts and maybe associated with adv
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Completion of h of education was significant in virtually
2020-07-25
Completion of 150 h of education was significant in virtually all prior studies of the 150-h requirement (Allen and Woodland, 2006, Boone et al., 2006 and others). While the 150-h requirement applies to licensure, students are often permitted (as in California) to sit for the CPA exam with fewer tot
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