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br Materials and methods br
2021-08-26
Materials and methods Results The monoclonal antibody (mAb), 12G5, reacts specifically with the human fusin protein and recognizes the protein on many T-cell lines such as the SUP-T1 Nitecapone (Endres et al., 1996). As shown in Fig. 1, AMD3100 at 25 μg/ml completely inhibited the binding of
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Injurious effects of cigarette smoke CS
2021-08-26
Injurious effects of cigarette smoke (CS) on human health are progressively being acknowledged both in animal and human studies. CS is a highly complex mixture that contains substantive amounts of toxic oxidants, nitric oxide, organic compounds, free radicals and microbial cell components including
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br Conclusions Enzyme can be
2021-08-26
Conclusions Enzyme can be delivered to the tumour by using humanised or fully human MJ33 lithium salt or even loaded into synthetic nanospheres produced from silica [64] or liposomally entrapped [65]. For any future ADEPT developments, a number of basic points need to be considered. As immunogeni
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Errors are detected by comparing the output data against
2021-08-26
Errors are detected by comparing the output data against an error free reference. After error detection, the process is restarted so that only one error is accounted. The susceptibility is inferred by the ratio between injected events and detected errors: = 100×errors÷events%. Error rates are obtai
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Though limited to a large cohort of self reported healthy
2021-08-26
Though limited to a large cohort of self-reported healthy individuals, associations between individual autophagy pathway have been identified which may be clinically significant. Though slight, there is a relationship between the CYP2D6-inferred metabolizer phenotype and the diplotype-predicted act
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The oxidation of the lipid fraction
2021-08-26
The oxidation of the lipid fraction of meat is an extremely complex process because of the high sensitivity of oxidation products to decomposition, their reactions with other components, the complex effect of catalysts and the presence of antioxidants. These changes are the main cause of limited she
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Data on optimal hormone formulations routes of
2021-08-26
Data on optimal hormone formulations, routes of administration, doses and duration of hormone use in young women with POF are lacking (Box 1). Transdermal teniposide administration, which avoids the first-pass hepatic circulation and the increase in inflammatory markers such as C-reactive protein,
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What is the predominant mechanism underlying the benefits of
2021-08-26
What is the predominant mechanism underlying the benefits of udenafil, i.e. the vascular vs. myocardial effect? Lewis et al. suggested that the benefit of sildenafil in HFrEF would be derived from augmented RV systolic function that mainly results from pulmonary vasodilation, suggestive of the ‘vasc
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α-Cyperone br In some but not all human vessels a small
2021-08-25
In some, but not all, human vessels, a small population of ETB (usually α-Cyperone with atherosclerotic lesions did not show any increase. In agreement, in experimental medicine studies in both heart failure patients and volunteer controls, selective ETA antagonism (BQ123) caused the expected pote
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Introduction Ubiquitylation is a post
2021-08-25
Introduction Ubiquitylation is a post-translational modification which impacts almost every biological process in the cell. Dysregulation of the ubiquitylation pathway is associated with several diseases, including cancer, neurodegenerative disorders, and immunological dysfunctions. Single ubiquiti
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Poxviruses have double stranded DNA dsDNA genomes yet they
2021-08-25
Poxviruses have double-stranded DNA (dsDNA) genomes, yet they replicate within the cytoplasm. Poxviruses that cause human disease include monkeypox virus (Reynolds et al., 2004), molluscum contagiosum virus (Hanson and Diven, 2003) and variola virus (VARV), the cause of smallpox, a disease eradicate
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Db model cells showed various aberrant phenotypes that seeme
2021-08-25
Db model cells showed various aberrant phenotypes that seemed to reflect the pathological abnormalities found under diabetic conditions. First, in Db model cells after insulin stimulation, we found the inhibition of the transcriptional repression of the gluconeogenic genes, PCK1 and G6PC, and aberra
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br Introduction In most of the angiosperms
2021-08-25
Introduction In most of the angiosperms, sexual reproduction requires a process called double fertilization where the specialized cell division called meiosis produces haploid gametes combine to form diploid (2n) embryo. In mitoxantrone to this, apomixis, naturally occurs in at least 400 plant f
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NMR was employed for the determination
2021-08-25
NMR was employed for the determination of un-ligated domain 1 structure of DDR2 receptor. The collagen-binding site on the same was identified by cross saturation experiment and mutagenesis [40]. Birgit leitinger identified the binding site of collagen with DDR2 receptor, which was three spatially a
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Interestingly ASV infusion in the dRN of saline pre
2021-08-25
Interestingly, ASV-30 infusion in the dRN of saline pre-treated rats had no effect on anxiety-like behaviors. This result may be due to the saline pre-treated group exhibiting relatively low levels of anxiety-like behaviors (when compared to saline pre-treated rat of the first experiment that were n
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