• Introduction Tumor necrosis factor TNF is

  2020-07-28

  

  Introduction Tumor necrosis factor (TNF) is a pro-inflammatory mediator with the capacity to induce apoptosis (Benderska et al., 2012). Recent reports have shown that TNF might trigger cell death, at least in part, by directly affecting the reorganization of the glut 1 cytoskeleton (Campos et al.,

• Numerous studies indicate that plant cysteine

  2020-07-28

  

  Numerous studies indicate that plant cysteine proteases from the papain family (C1A) are crucial in degradation and mobilization of storage proteins in cereal seeds (Mikkonen et al., 1996, Prabucka and Bielawski, 2004, Shi and Xu, 2009). The increasing activity of these proteases during the ongoing

• In conclusion adipose PGD suppressed the lipolysis by decrea

  2020-07-28

  

  In conclusion, adipose PGD2 suppressed the lipolysis by decreasing the intracellular cAMP level through DP2R. Therefore, PGD2 enhanced adipocyte differentiation (lipid accumulation) through both repression of the lipolysis via DP2R and activation of the lipogenesis via PPARγ. Thus, L-PGDS and DP2R a

• Adrenocortical steroids release by the

  2020-07-28

  

  Adrenocortical steroids release by the adrenal gland is directly regulated by CRF (Nussdorfer, 1996) through its receptors, predominantly CRF1r (Müller et al., 2001). In the adrenal gland, PFOS at the dose of 0.5 mg/kg/day activates CRF1r gene expression while the doses of 3.0 and 6.0 mg/kg/day stim

• Several different information items can be recommended

  2020-07-28

  

  Several different information items can be recommended to support the software engineer in his/her task according to his/her needs. These items types include source code within a project, reusable source code, code examples, operations and people (Robillard et al., 2014). We witness several works on

• Finally the presence of the

  2020-07-28

  

  Finally, the presence of the recombinant hydroxylated sponge collagen polypeptide was detected in the colCH4 strain by MS-analysis using a TripleTOF instrument and allowing to confirm the ability of the recombinant sponge P4H to display its catalytic activity inside the yeast cell on its natural sub

• Chemical cytometry utilizes sensitive analytical techniques

  2020-07-27

  

  Chemical cytometry utilizes sensitive analytical techniques such as microelectrophoresis or mass spectrometry to analyze and characterize the contents of single autumn wind (Dovichi, 2010; Dovichi & Hu, 2003). Microelectrophoretic chemical cytometry is well-suited to address many of the challenges

• Fig shows optical microscopy images of the nanocomposite

  2020-07-27

  

  Fig. 1 shows optical microscopy images of the nanocomposite surfaces at increasing concentration of GNP-DNA filler, indicating a clear improvement of the surface homogeneity at higher loading. Larger 46619 australia are present in the nanocomposite with 20 wt% of GNP-DNA with brighter and darker re

• br New methods to investigate responses at

  2020-07-27

  

  New methods to investigate responses at low-dose exposures Alkylating agents DNA repair and break point doses Interactions between DNA repair and DDR pathways Profiling of biological pathways and genotoxic dose–response relationships Conclusions There is significant interest in und

• L AmDH and parent LeuDH

  2020-07-27

  

  L-AmDH and parent LeuDH differed in response to increasing solution viscosity, indicating a change in the rate-limiting steps of catalysis. For LeuDH, both the amination and deamination directions showed an inverse hyperbolic viscosity effect on normalized appkcat/KM value for the amino/amino (±)-J

• Our studies investigating a role for integrins in collagen

  2020-07-27

  

  Our studies investigating a role for integrins in collagen induction of lysyl oxidase may also suggest a cooperative function for integrins in DDR2-mediated up-regulation of lysyl oxidase by collagen. It is interesting to note, however, that the level of 32kDa lysyl oxidase in the presence of EDTA w

• br DDR receptor in cross

  2020-07-27

  

  DDR2 receptor in cross talking mechanism at joints Cross talking pathway provides us a better understanding of the chondrocytes behavior as chondrocytes expressed several receptors that get activated by components of an extracellular matrix upon damage in articular cartilage. DDR2 receptor in OA

• br Acknowledgments The authors thank Elisabete Lepera and

  2020-07-27

  

  Acknowledgments The authors thank Elisabete Lepera and Rosana Silva for technical support. The study was supported by FAPESP, CNPq and PADC/FCF-UNESP. T.T. Miguel was the recipient of a FAPESP (Proc. 05/05171-1) and R.L. Nunes-de-Souza of a CNPq (Proc. 303580/2009-7) fellowship. Introduction

• The conditioned place aversion CPA paradigm is

  2020-07-27

  

  The conditioned-place aversion (CPA) paradigm is a highly sensitive animal model for measurement of the negative affective component of drug withdrawal, as well as for investigating neural substrates underlying the aversive memory associated with withdrawal (Myers et al., 2012; Stinus et al., 2000).

• Most diagnostic tests for the detection of Aspergillus and o

  2020-07-27

  

  Most diagnostic tests for the detection of Aspergillus and other fungi utilise serum and bronchoalveolar lavage (BAL) fluid for the confirmation of pulmonary aspergillosis and acute invasive aspergillosis (Agarwal et al., 2015). BAL requires bronchoscopy that is invasive and may be difficult to obta

15829 records 818/1056 page Previous Next First page 上5页 816817818819820 下5页 Last page